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Clinical trial results support IPL therapy

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Jeff Megahan

Researchers at Auckland University have found that intense pulsed light (IPL) therapy is an effective treatment for meibomian gland dysfunction and related eye disease.

A prospective, double-masked, placebo-controlled, pair-eye clinical trial on the use of IPL technology for the treatment of meibomian gland dysfunction was conducted in New Zealand, by Associate Professor Jennifer Craig.

In the study, 28 participants underwent IPL treatment (E > Eye) in one eye along with a placebo treatment in the partner eye. Treatments were administered at one, 15 and 45 days following baseline evaluation. It was found that lipid layer grades improved significantly from baseline in the treated eyes (p < 0.001), but not the control eye (p = 0.714) with 82 per cent of treated eyes improving by at least one lipid layer grade. It was also found that non-invasive tear break-up time improved significantly from baseline to day 45 in the treated eye (p < 0.001), but not the control eye (p = 0.056).

The authors concluded that IPL with multiple sculpted pulses shows therapeutic potential for meibomian gland dysfunction, improves tear film quality and reduces symptoms of dry eye.



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